简体中文
1. Team/Teaching and Research Office/discipline/branch introduction
1.1 Description of the team, teaching and research department, and discipline
The Department of Toxicology of Zhengzhou University was established in 1978. In 2003, it was authorized to grant master's degree, and in 2004, it officially enrolled master's degree students. The teaching and Research Department has 6 faculty members, including 2 professors, 1 associate professor, 1 associate researcher, 1 lecturer and 1 full-time postdoctoral fellow. 100% of the faculty has a PhD degree. It undertakes the courses of "Fundamentals of Toxicology" for undergraduates of preventive medicine and medical laboratory majors, "Hygiene" for clinical medicine majors, and the courses of "Molecular Toxicology" and "Experimental Techniques and Methods of Toxicology" for postgraduates. Two teachers from the Teaching and Research Department won the first prize in the Teaching competition of Henan Education System and the title of "Teaching pacesetter of Henan Province".
The main academic research areas of the faculty include environmental toxicology, respiratory toxicology, neurotoxicology, molecular and genetic toxicology, food toxicology, computational toxicology, immunotoxicology, radiation toxicology, and drug toxicology. Focusing on the construction of a healthy China, teachers have adopted new technologies such as organoid construction, single-cell sequencing, nanosensors and gene chips, and successively carried out toxic effects caused by heavy metals, pesticides, coal coke asphalt, cigarette smoke, air pollutants (PM2.5, ozone, microplastics), new pollutants, as well as climate change, social environmental factors, indoor environment, etc. The research on the mechanism of poisoning, early diagnosis, the preparation and targeted delivery of stem cells, nanomedicine and other therapeutic measures has formed a high-level academic team.
At present, there are 5 National Natural Science Foundation projects, Henan Province and Zhengzhou City science and technology research projects. "Biological monitoring index of Occupational lung cancer high-risk population and intervention experiment of garlic", "Reproductive toxicity of metal mercury and its effect on offspring intelligence Development" and "Study on chromosomal instability of Bronchial epithelial cells induced by coal tar asphalt" were awarded the second prize of Henan Province Science and Technology Progress Award in 1996, 1999 and 2014 respectively. In recent years, the research group has focused on the toxic effects caused by climate change, social and environmental factors in the post-epidemic era, new indoor and outdoor pollutants, polycyclic aromatic hydrocarbons and cigarette smoke, including respiratory toxicology, neurotoxicology and reproductive toxicology, and adopted a series of new technologies and methods to explore the mechanism of toxic action. Intervention and treatment are carried out through probiotic preparations and regulation of intestinal microbial diversity, preparation and targeted delivery of nanomedicine, etc., to contribute to improving and protecting the environment and improving the quality of human life. In recent years, this discipline has published more than 150 academic papers, published more than 20 books, and won more than 20 awards for various achievements. Graduate students and undergraduates have won national scholarships, provincial May Day Labor MEDALS, provincial Merit students, provincial and university-level excellent graduation papers.
Teaching and research department teacher invention patent
Patent name |
Patent class |
Inventor |
Rapid inhalation tracheal infusion delivery system |
Authorized invention patent |
Feng Feifei et al |
A polypeptide binding to JE virus E protein and its application |
Authorized invention patent |
Fan Jianming et al |
National Natural Science Foundation project undertaken by teachers of the Teaching and Research Department
Project name |
Project source |
Host |
The transformation effect of Rap2B gene overexpression on human bronchial epithelial cells and the effect of cigarette smoke condensate on RAP2B gene |
National Natural Science Foundation project |
Zhang Qiao |
Toxicology and mechanism of synergistic effect of ozone and high temperature on respiratory tract injury in children |
National Natural Science Foundation project |
Feng Feifei |
Identification and functional analysis of host mirnas associated with Japanese encephalitis virus infection |
National Natural Science Foundation project |
Feng Feifei |
The role of NLRP3 inflammasome in promoting the occurrence of lung cancer induced by bacterial lipopolysaccharide and coal tar pitch and its mechanism The effect and mechanism of environmental exposure during pregnancy on children's mental health |
National Natural Science Foundation Youth Fund project |
Feng Feifei |
National Natural Science Foundation Youth Fund project |
Xue Yuan |
2. Team/Teaching and Research section/discipline/branch composition
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Head of the Department of Health Toxicology: Professor Zhang Qiao, born in 1965, Doctor, master tutor. He is currently the director of the Chinese Society of Environmental Mutagen, the member of the Professional Committee of Risk Assessment and the member of the Professional Committee of Anticancer; Member of Chinese Society of Toxicology; Member of Toxicology Committee, Chinese Preventive Medical Association. He is mainly engaged in the research of molecular toxicology of carcinogenic factors and the relationship between environmental harmful factors and health. |
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Deputy Director of the Teaching and Research Department (Chair) : Professor Feng Feifei, born in 1983, Doctor, doctoral supervisor. He is currently a member of the Chinese Society of Toxicology, a member of the Chinese Society of Environmental Mutagen, and a member of the Youth Committee of the Chinese Society of Health Toxicology, Preventive Medical Association. Mainly engaged in air pollutants, new pollutants, climate and other environmental toxicology; Chemical carcinogenic mechanism and treatment; Stem cells; Nutrient intervention and other aspects of research. |
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Associate Professor Fan Jianming, born in 1971, Doctor, master tutor. He is mainly engaged in molecular toxicology research. |
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Shen Xinming, Associate researcher, born in 1994, PhD. His research field is environmental chemistry and environmental toxicology. His research interests include screening and analysis of new pollutants, prediction of toxicity and risk of new pollutants by machine learning, health effects and molecular mechanisms of new pollutants. |
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Xue Yuan, Lecturer, born in 1989, Doctor, master tutor. Research interests: The harm of environmental pollution to brain health, including social environmental factors, indoor and outdoor environment and food environment. |
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Postdoctoral Liu Ni, born in 1989, PhD. Research interests: Environment and life cycle brain (mental) health, nanomedicine synthesis and precision delivery, early diagnosis and treatment of neurodegenerative diseases. |
2、Personalized page - Team/Teaching and Research room style display
Teaching and research department to teach undergraduate students to complete the preventive medicine professional practice
Toxicology teacher and graduate student
Toxicology teachers and graduates
