论文

[1] Zhao Y, Qu Y, Duan M, Hao C, Yao W. Dynamics of the inhibitory immune checkpoint TIM-3 in mouse pulmonary phagocytes after silica exposure. Ecotoxicol Environ Saf. 2023;261:115087.

[2] Qu Y, Zhai R, Wang D, Wang Z, Hou G, Wu C, Tang M, Xiao X, Jiao J, Ba Y, Zhou F, Qiu J, Yao W. Mitochondrial folate pathway regulates myofibroblast differentiation and silica-induced pulmonary fibrosis. J Transl Med. 2023 Jun 6;21(1):365.

[3] Deng M, He J, Hao C, Guo Y, Si H, Deng X, Zhang C, Li S, Yao S, Ren W, Yao W. Effect of exosomes derived from bone marrow mesenchymal stem cells on programmed cell death in blast-induced lung injury in rats. Shock. 2023;59(6):955-965.

[4] Zhao Y, Qu Y, Hao C, Yao W. PD-1/PD-L1 axis in organ fibrosis. Front Immunol. 2023;14:1145682.

[5] Deng X, Niu Z, Hao C, Lin J, Yao W. HMGB1 coordinates with Brahma-related gene 1 to promote epithelial-mesenchymal transition via the PI3K/Akt/mTOR pathway in BEAS-2B cells. Exp Cell Res. 2023;424(2):113522.

[6] Tian Y, Xia J, Yang G, Li C, Qi Y, Dai K, Wu C, Guo Y, Yao W, Hao C. A2aR inhibits fibrosis and the EMT process in silicosis by regulating Wnt/β-catenin pathway. Ecotoxicol Environ Saf. 2023;249:114410.

[7] Dai K, Wang C, Yao W, Hao C. Expression level and function analysis of serum miRNAs in workers with occupational exposure to benzene series. Chemosphere. 2023;313:137460.

[8] Guo Y, Deng X, Dai K, Deng M, He J, Si H, Xu X, Niu Z, Wang C, Yao W, Hao C. Benchmark dose estimation based on oxidative damage in Chinese workers exposed to benzene series compounds. Environ Toxicol Pharmacol. 2023;100:104150.

[9] Xia J, Tian Y, Shao Z, Li C, Ding M, Qi Y, Xu X, Dai K, Wu C, Yao W, Hao C. MALAT1-miR-30c-5p-CTGF/ATG5 axis regulates silica-induced experimental silicosis by mediating EMT in alveolar epithelial cells. Ecotoxicol Environ Saf. 2023;249:114392.

[10] Ding M, Pei Y, Zhang C, Qi Y, Xia J, Hao C, Yao W. Exosomal miR-125a-5p regulates T lymphocyte subsets to promote silica-induced pulmonary fibrosis by targeting TRAF6. Ecotoxicol Environ Saf. 2023;249:114401.

[11] Li X, Zhao C, Li C, Zhang M, Xie Y, Feng F, Yao W, Wang N. Detection and analysis of lung microbiota in mice with lung cancer lacking the NLRP3 gene. Biochem Biophys Res Commun. 2023;639:117-125.

[12] Zhou R, Jin C, Jiao L, Zhang S, Tian M, Liu J, Yang S, Yao W, Zhou F. GGA (geranylgeranylacetone) ameliorates bleomycin-induced lung inflammation and pulmonary fibrosis by inhibiting apoptosis and oxidative stress. Mol Biol Rep. 2023;50(9):7215-7224.

[13] Zhou R, Jin C, Jiao L, Zhang S, Tian M, Liu J, Yang S, Yao W, Zhou F. Geranylgeranylacetone, an inducer of heat shock protein 70, attenuates pulmonary fibrosis via inhibiting NF-κB/NOX4/ROS signalling pathway in vitro and in vivo. Chem Biol Interact. 2023;382:110603.

[14] Zhao Y, Hao C, Li M, Qu Y, Guo Y, Deng X, Si H, Yao W. PD-1/PD-L1 inhibitor ameliorates silica-induced pulmonary fibrosis by maintaining systemic immune homeostasis. Biomed Pharmacother. 2022 Apr;148:112768.

[15] Y Qu, Bao L., Zhao Y., Li Y., Ding M., Hao C., Yao W. Dendritic cells activated by cimetidine induce Th1/Th17 polarization in vitro and in vivo [J]. Toxicol In Vitro, 2022, 83(105395.

[16] Liu S, Yao W. Prediction of lung cancer using gene expression and deep learning with KL divergence gene selection. BMC Bioinformatics. 2022;23(1):175.

[17] Li Y, Cheng Z, Fan H, Hao C, Yao W. Epigenetic Changes and Functions in Pneumoconiosis. Oxid Med Cell Longev. 2022;2022:2523066.

[18] Deng X, Hao C, Li Y, Guo Y, Si H, He J, Deng M, Niu Z, Wang C, Xu X, Dai K, Yao W. Lysophosphatidylcholine acyltransferase 1 alleviates silica-induced pulmonary fibrosis by modulating lipid metabolism. Biomed Pharmacother. 2022;155:113638.

[19] Bao L, Hao C, Wang J, Guo F, Geng Z, Wang D, Zhao Y, Li Y, Yao W. In vitro co-culture model of human monocyte-derived dendritic cells and T cells to evaluate the sensitization of dinitrochlorobenzene. Ecotoxicol Environ Saf. 2021 Sep 1;220:112331.

[20] Zhao Q, Hao C, Wei J, Huang R, Li C, Yao W. Bone marrow-derived mesenchymal stem cells attenuate silica-induced pulmonary fibrosis by inhibiting apoptosis and pyroptosis but not autophagy in rats. Ecotoxicol Environ Saf. 2021 Apr 10;216:112181.

[21] Huang R, Hao C, Wang D, Zhao Q, Li C, Wang C, Yao W. SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation. Toxicol Appl Pharmacol. 2021 Jul 1;422:115559.

[22] Wei J, Zhao Q, Yang G, Huang R, Li C, Qi Y, Hao C, Yao W. Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition. J Cell Mol Med. 2021 Jun 2;25(13):6417–28.

[23] Wu Yao; Peiyan Yang; Yuanmeng Qi; Luheng Jin; Ahui Zhao; Mingcui Ding; Di Wang; YiPing Li;Changfu Hao*; Transcriptome analysis reveals a protective role of liver X receptor alpha against silica particle-induced experimental silicosis,Science of the Total Environment, 2020, 747: 141531.

[24] Qu YQ, Hao CF, Zhai RN, Yao W. Folate and macrophage folate receptor-beta in idiopathic pulmonary fibrosis disease: the potential therapeutic target?. Biomed Pharmacother. 2020; 131: 110711.

[25] Wang D, Hao CF, Zhang L, Zhang JH, Liu SN, Li YP, Qu YQ, Zhao YL, Huang RX, Wei JJ, Yao W. Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation. Ecotoxicol Environ Saf. 2020; 192: 110253.

[26] Zhao YL, Hao CF, Bao L, Wang D, Li YP, Qu YQ, Ding MC, Zhao AH, Yao W. Silica particles disorganize the polarization of pulmonary macrophages in mice. Ecotoxicol Environ Saf. 2020; 193: 11.364.

[27] Yao W, Ding MC, Bao L, Zhao YL, Wang D, Li YP, Qu YQ, Hao CF. Human monocyte-derived dendritic cells as an in vitro alternative model cell to evaluate the immunotoxicity of 2, 4-Dinitrochlorobenzene. Toxicology letters. 2020, 330: 118-127.

[28] Wu JJ, Wang HX*, Yao W*, Yan Z, Pei JJ. Late-life depression and the risk of dementia in 14 countries: a 10-year follow-up study from the Survey of Health, Ageing and Retirement in Europe. Journal of affective disorders. 2020; 274: 671-677.

[29] Bao L, Hao CF, Wang J, Wang D, Zhao YL, Li YP, Yao W. High-Dose Cyclophosphamide Administration Orchestrates Phenotypic and Functional Alterations of Immature Dendritic Cells and Regulates Th Cell Polarization. Frontiers in pharmacology. 2020; 11: 775.

[30] Liu SN, Hao CF, Bao L, Zhao DH, Zhang HY, Hou JY, Wang D, Chen HT, Feng FF, Yao W. Silica Particles Mediate Phenotypic and Functional Alteration of Dendritic Cells and Induce Th2 Cell Polarization. Frontiers in Immunology. 2019;10.

[31] Qiao YM, Lu YK, Yan Z, Yao W*, Pei JJ, Wang HX*. Reciprocal associations between job strain and depression: A 2-year follow-up study from the Survey of Health, Ageing and Retirement in Europe. Brain and behavior. 2019, 9(9): e01381.

[32] Zhao YL, Hao CF, Zhai RN, Bao L, Wang D, Li YP, Yu XH, Huang RX, Yao W. Effects of cyclophosphamide on the phenotypes and functions of THP-1 cells. Environ Toxicol Pharmacol. 2019; 70: 103201.

[33] Yu XH, Zhai RN, Hua BY, Bao L, Wang D, Li YP, Yao W*, Fan H*, Hao CF*. miR-let-7d attenuates EMT by targeting HMGA2 in silica-induced pulmonary fibrosis. Rsc advances. 2019; 9(34): 19355-19364.

[34] Bao L, Hao CF, Liu SN, Zhang L, Wang J, Wang D, Li YP, Yao W*. Dendritic cells trigger imbalance of Th1/Th2 cells in silica dust exposure rat model via MHC-II, CD80, CD86 and IL-12. Rsc Advances. 2018;8(46):26108-26115.

[35] Zhang L, Hao CF, Yao SQ, Tang R, Guo W, Cong HB, Li JF, Bao L, Wang D, Li YP, Yu XH, Duan SY, Yao W*. Exosomal miRNA Profiling to Identify Nanoparticle Phagocytic Mechanisms. Small. 2018;14(15).

[36] Zhang L, Hao CF, Zhai RN, Wang D, Zhang JH, Bao L, Li YP, Yao W*. Downregulation of exosomal let-7a-5p in dust exposed- workers contributes to lung cancer development. Respiratory Research. 2018;19.

[37] Zhang L, Li JF, Hao CF, Guo W, Wang D, Zhang JH, Zhao YL, Duan SY, Yao W*. Up-regulation of exosomal miR-125a in pneumoconiosis inhibits lung cancer development by suppressing expressions of EZH2 and hnRNPK. Rsc Advances. 2018;8(47):26538-26548.

著作

[1]姚武（编委），预防医学（第二版），人民卫生出版社，2022

[2]姚武（编委），预防医学（第四版），人民卫生出版社，2023

[3]姚武（编委），职业卫生与职业医学（第八版），人民卫生出版社，2017

[4]姚武（编委），职业卫生与职业医学（第七版），人民卫生出版社，2012

[5]姚武（编委），卫生法律制度与监督学（第三版），人民卫生出版社，2013

[6]姚武（编委），预防医学（7、8年制临床医学专业使用，第二版），人民卫生出版社，2015

[7]姚武（副主编），卫生法学纲要，复旦大学出版社（第五版），2014