论文

[1]Xinxin Yuan, Wenchao Geng, Jiangying Ji, Zhiyi Yan, Jiarui Wei, Yongjun Wu, Ruiying Yang*. CRISPR/Cas13a-Programmed Cu NCs and Z-Scheme T-COF/Ag2S for Photoelectrochemical Biosensing of circRNAs. ACS Sensors 2025, 10, 1270–1279 (中科院SCI一区 IF=8.2)

[2]Ruiying Yang*, Jiangying Ji, Lihua Ding, Xinxin Yuan, Lingbo Qu, Yongjun Wu*, Yuling Li*. CRISPR-Enhanced Photocurrent Polarity Switching for Dual-lncRNA Detection Combining Deep Learning for Cancer Diagnosis. Analytical Chemistry 2024, 96, 13278−13284. (中科院SCI一区 IF=6.7)

[3]Wenchao Geng, Guihua Jiang, Huimin Liu, Linsheng Xue, Lihua Ding, Yuling Li, Yongjun Wu, Ruiying Yang*. A Direct-Contact Photocurrent-Direction- Switching Biosensing Platform Based on In Situ Formation of CN QDs/TiO2 Nanodiscs and Double-Supported 3D DNA Walking Amplification. Small 2023, 19, 2302829. (中科院SCI一区 IF=13.3)

[4]Ruiying Yang, Guihua Jiang, Huimin Liu, Leiliang He, Fei Yu, Li’e Liu, Lingbo Qu, Yongjun Wu*. A dual-model “on-super off” photoelectrochemical/ratiometric electrochemical biosensor for ultrasensitive and accurate detection of microRNA-224. Biosensors Bioelectronics 2021, 188, 113337. (中科院SCI一区 IF=12.6)

[5]Yuling Li1, Li-e Liu1, Hangchen Han, Xinxin Yuan, Jiangying Ji, Linsheng Xue, Yongjun Wu, Ruiying Yang*. A signal-switchable photoelectrochemical biosensor for ultrasensitive detection of long non-coding RNA in cancer cells. Talanta 2024, 273, 125878. (中科院SCI一区 IF=6.1)

[6]Li-e Liu, Linsheng Xue, Yuling Li, Jiangying Ji, Xinxin Yuan, Hangchen Han, Lihua Ding, Yongjun Wu, Ruiying Yang*. MOFs-derived Co3O4@MnO2@Carbon dots with enhanced nanozymes activity for photoelectrochemical detection of cancer cells in whole blood. Talanta 2024, 266, 125095. (中科院SCI一区 IF=6.1)

[7]Wenchao Geng, Linsheng Xue, Yuling Li, Jiangying Ji, Xinxin Yuan, Lihua Ding, Ruiying Yang*. A dual-model immobilization-free photoelectrochemical/visual colorimetric bioanalysis based on microemulsion self-assemblies mediated multifunctional signal amplification strategy. Analytica Chimica Acta 2023, 1277, 341644. (中科院SCI一区 IF=6.2)

[8]Guihua Jiang, Huimin Liu, Jie Liu, Li’e Liu, Yuling Li, Linsheng Xue, Yongjun Wu, Ruiying Yang*. Engineering of multifunctional carbon nanodots-decorated plasmonic Au@Ag nanoenzymes for photoelectrochemical biosensing of microRNA-155. Sensors and Actuators: B. Chemical 2022, 360, 360, 131653. (中科院SCI一区 IF=9.2)

[9]Huimin Liu, Guihua Jiang, Li-e Liu*, Linsheng Xue, Yuling Li, Yongjun Wu, Ruiying Yang*. Multicomponent Cu@Cu2O@C hybrid-induced photocurrent polarity switching biosensing strategy for the detection of TK1 mRNA. Sensors and Actuators: B. Chemical 2022, 372, 132631. (中科院SCI一区 IF=9.2)

[10]Guihua Jiang1, Ruiying Yang1, Jie Liu, Huimin Liu, Li’e Liu, Yongjun Wu*, Youmei A*. Two-dimensional Ti2C MXene-induced photocurrent polarity switching photoelectrochemical biosensing platform for ultrasensitive and selective detection of soluble CD146. Sensors and Actuators: B. Chemical 2022, 350, 130859. (中科院SCI一区 IF=9.2)

[11]Ruiying Yang, Guihua Jiang, Jie Liu, Yilin Wang, Ningge Jian, Leiliang He, Li’e Liu, Lingbo Qu, Yongjun Wu*. Plasmonic TiO2@Au NPs//CdS QDs photocurrent-direction switching system for ultrasensitive and selective photoelectrochemical biosensing with cathodic background signal. Analytica Chimica Acta 2021, 1153, 338283. (中科院SCI一区 IF=6.9)

[12]Ruiying Yang*, Jie Liu. Sensitive and selective photoelectrochemical immunosensing platform based on potential-induced photocurrent-direction switching strategy and a direct Z-scheme CdS//hemin photocurrent-direction switching system. Journal of Electroanalytical Chemistry 2020, 873, 114346. (中科院SCI二区 IF=4.5)

[13]Wenchao Geng, Ruiying Yang*. A triple-helix molecular switch photoelectrochemical biosensor for ultrasensitive microRNA detection based on position-controllable CdS//CdTe signal enhancement and switching. Chemical Communications 2020, 56, 2909–2912. (中科院SCI二区 IF=6.2)

[14]Ruiying Yang, Kang Zou, Xiaohua Zhang, Cuicui Du, Jinhua Chen*. Target-induced photocurrent-polarity switching: a highly selective and sensitive photoelectrochemical sensing platform. Chemical Communications 2019, 55, 8939–8942. (中科院SCI一区 IF=6.2)

[15]Ruiying Yang, Kang Zou, Xiaohua Zhang, Cuicui Du, Jinhua Chen*. A new photoelectrochemical immunosensor for ultrasensitive assay of prion protein based on hemin-induced photocurrent direction switching. Biosensors Bioelectronics 2019,132, 55-61. (中科院SCI一区 IF=12.6)

[16]Ruiying Yang, Kang Zou, Yanmei Li, Leixia Meng, Xiaohua Zhang, Jinhua Chen*. Co3O4-Au Polyhedra: A Multifunctional Signal Amplifier for Sensitive Photoelectrochemical Assay. Analytical Chemistry 2018, 90, 9480–9486. (中科院SCI一区 IF=7.4)

[17]Ruiying Yang, Yanmei Li, Kang Zou, Leixia Meng, Xiaohua Zhang, Jinhua Chen*. A label-free and blocker-free photoelectrochemical strategy for highly sensitive caspase-3 assay. Chemical Communications 2018, 54, 4830–4833. (中科院SCI一区 IF=6.2)

[18]Ruiying Yang, Xiaoxia Yan, Yanmei Li, Xiaohua Zhang, Jinhua Chen*. Nitrogen-Doped Porous Carbon-ZnO Nanopolyhedra Derived from ZIF-8: New Materials for Photoelectrochemical Biosensors. ACS Applied Materials Interfaces 2017, 9, 42482–42491. (中科院SCI一区 IF=9.5).

发明专利

[1]杨瑞英; 耿文超; 原鑫鑫; 季江颖; 严志怡; 魏嘉芮; 吴拥军; 何磊良; 丁丽华. 基于CRISPR和HCR原位生成铜纳米簇的可再生生物传感器及其在检测circRNA中的应用, 2024-07-15, 中国, CN202410943779.4

[2]杨瑞英; 耿文超; 薛林生; 吴拥军; 余增丽; 丁丽华; 季江颖; 原鑫鑫; 严志怡. 基于多功能纳米酶和 EXO III-DNAzyme 的循环肿瘤细胞光电化学传感器, 2024-06-18, 中国, CN202410788645.X

[3]杨瑞英; 李玉玲; 季江颖; 丁丽华; 原鑫鑫; 严志怡; 薛林生; 吴拥军. CRISPR光电流极性翻转生物传感器及其在联合检测lncRNAs中的应用, 2023-12-29, 中国, CN117925834A

[4]杨瑞英; 刘慧敏; 薛林生; 李玉玲; 原鑫鑫; 季江颖; 刘利娥; 丁丽华; 吴拥军. 双金属氧化物及其制备方法和信号翻转检测抗生素的应用, 2023-06-30, 中国, 已授权，专利号：ZL 202310795134.6

[5]杨瑞英; 苏纾瑶; 薛林生; 李玉玲; 刘慧敏; 刘利娥; 吴拥军. 人工酶检测肿瘤细胞的传感器及其制备方法和应用, 2024-03-12, 中国, 已授权，专利号：ZL 202210711574.4

[6]杨瑞英; 蒋桂花; 刘慧敏; 刘利娥; 阿有梅; 吴拥军. 检测癌症标志物的信号翻转型光电化学生物传感器及其制备方法和应用, 2022-01-06, 中国，已授权，专利号：ZL 202210010986.5

会议报告

[1]第五届全国卫生检验与检疫专业学科建设与人才培养高层次论坛（2023年，衡阳），大会报告

[2]中国化学会第十五届全国电分析化学学术会议（2023年，扬州），大会报告

[3]第二届环境与健康分析化学前言论坛（2023年，南京），大会报告

其他

[1]2024年，指导本科生获省级级大学生创新创业训练计划项目1项

[2]2024年，指导本科生在第十二届“挑战杯”大学生创业计划竞赛中荣获校级二等奖1项

[3]杨瑞英, 刘利娥, 阿有梅, 刘洁, 吴拥军. 2024年，河南省教育厅优秀科技论文，一等奖

[4]杨瑞英, 刘利娥, 2023年，河南省教育科学研究优秀成果奖，二等奖