代表性论文

[1] Ruiying Yang, Jiangying Ji, Lihua Ding, Xinxin Yuan, Lingbo Qu, Yongjun Wu*, and Yuling Li*.CRISPR-enhanced photocurrent polarity switching for dual-lncRNA detection combining deep Learning for cancer diagnosis. Analytical Chemistry, 2024, 96:13278−13284.

[2] Yan Wu, Zibo Gao, Yaru Chai, Aiai Zhang, Sitian He, Xia Liu, Huijie Yuan, Longlong Tan, Lihua Ding*, Yongjun Wu*. One-step and label-free ratiometric fluorescence assay for the detection of plasma exosome towards cancer diagnosis. Talanta, 2024, 271: 125700.

[3] Clement Yaw Effah, Lihua Ding, Longlong Tan, Sitian He, Xiang Li, Huijie Yuan, Yi Li, Shaohua Liu, Tongwen Sun*, Yongjun Wu*. A SERS bioassay based on vancomycin- modified PEI-interlayered nanocomposite and aptamer-functionalized SERS tags for synchronous detection of Acinetobacter baumannii and Klebsiella pneumonia. Food Chemistry, 2023, 423:136242.

[4] Lihua Ding, Xia Liu, Zhenzhong Zhang, Li-e Liu, Sitian He, Yan Wu,Clement Yaw Effah, Ruiying Yang, Aiai Zhang, Wensi Chen, Mubarak Yarmamat, Lingbo Qu*, Xiaonan Yang*,Yongjun Wu*.Magnetic-nanowaxberry-based microfluidic ExoSIC for affinity and continuous separation of circulating exosomes towards cancer diagnosis. Lab on a Chip, 2023, 23:1694.

[5] Lihua Ding, Yan Wu, Li-e Liu, Leiliang He, Songcheng Yu, Clement Yaw Effah, Xia Liu, Lingbo Qu*,Yongjun Wu*. Universal DNAzyme walkers-triggered CRISPR-Cas12a/Cas13a bioassay for the synchronous detection of two exosomal proteins and its application in intelligent diagnosis of cancer. Biosensors and Bioelectronics, 2023, 219:114827.

[6] Sitian He#, Lihua Ding#, Huijie Yuan, Gaofeng Zhao*, Xiaonan Yang*, Yongjun Wu*. A review of sensors for classification and subtype discrimination of cancer: Insights into circulating tumor cells and tumor-derived extracellular vesicles, Analytica Chimica Acta, 2023, 1244:340703.

[7] Sitian He, Songcheng Yu, Jinlan Wei, Lihua Ding, Xiaonan Yang*,Yongjun Wu*. New horizons in the identification of circulating tumor cells (CTCs): An emerging paradigm shift in cytosensors. Biosensors and Bioelectronics, 2022,203:114043.

[8] Sitian He, Songcheng Yu*, Yinhua Feng , Leiliang He , Lie Liu , Clement Yaw Effah,Yongjun Wu*. A digital immuno-PCR assay for simultaneous determination of 5-methylcytosine and 5-hydroxymethylcytosine in human serum. Analytica Chimica Acta, 2022, 1192:339321.

[9] Lihua Ding, Li-e Liu, Leiliang He, Clement Yaw Effah, Ruiying Yang, Dongxun Ouyang, Ningge Jian, Xia Liu, Yongjun Wu*, Lingbo Qu*. Magnetic-nanowaxberry-based simultaneous detection of exosome and exosomal proteins for the intelligent diagnosis of cancer. Analytical Chemistry, 2021,93(45):15200-15208.

[10] Lihua Ding, Xiaonan Yang, Zibo Gao, Clement Yaw Effah, Xiaoju Zhang, Yongjun Wu*, Lingbo Qu*.A holistic review of the state-of-the-art microfluidics for exosome separation: An overview of the current status, existing obstacles, and future outlook. Small, 2021, 17(29): 2007174.

著作

[1] 屈凌波, 吴拥军主编. 食品中有害物质快速分析选论, 郑州大学出版社, 2019

[2] 屈凌波,吴里根,王岸娜,吴拥军,申瑞玲,张康逸 编著.面制品储藏过程成分变化与控制，郑州大学出版社, 2019

[3] 屈凌波主编,吴拥军,李炎强 副主编. 新型功能材料设计及应用, 郑州大学出版社, 2014

[4] 屈凌波, 吴拥军主编. 化学发光分析技术及其在药品食品分析中的应用，化学工业出版社, 2012

授权专利

[1] 吴拥军，刘利娥，熊亚敏，玉崧成，于斐，何磊良，屈凌波，王华栋. 基于量子点荧光免疫检测DNMT1的方法，2017-08-29，中国，ZL 2016 1 0324656.8

[2] 吴拥军，董佳佳，韩润平，于斐，何磊良，刘利娥，玉崧成，王佳，田咏梅，王艺琳，屈凌波.化学发光酶联核酸适体同步检测VEGF与CEA的方法，2023-03-17，中国，ZL 2019 1 1317493.0

[3] 吴拥军，丁丽华，屈凌波，玉崧成，何磊良，刘利娥，王艺琳，王威.血浆外泌体浓度和外泌体膜蛋白浓度的同步检测方法，2023-07-21，中国，ZL 2021 1 1143245.6

软件著作权

[1] 吴拥军. 肺癌危险度评价系统 V1.0. 计算机软件著作权登记证（软著登字第1248915号）

[2] 吴拥军. 肺部肿瘤评测系统 V2.0.   计算机软件著作权登记证（软著登字第3263345号）

学术奖励

[1] 吴拥军,丁丽华,何磊良,刘利娥,熊亚敏,王威,苗丽君,王艺琳,王佳,原慧洁. 肺癌筛查与早期诊断关键技术研究及应用. 2024年河南省科学技术进步二等奖.

[2] 吴拥军,丁丽华，屈凌波. 医理工交叉学科博士生培养模式探索与实践. 2023年河南省教育科学研究优秀成果二等奖.

[3] 基于磁性纳米杨梅的外泌体分离ExoSIC芯片构建及其在癌症诊断中的应用. 2023年第十六届“挑战杯”河南省大学生课外学术科技作品竞赛一等奖，指导教师：丁丽华, 吴拥军.

[4] 2017年指导全国“互联网+”大学生创新创业项目“智能型肺癌精准筛查系统”获河南省一等奖 国家铜奖，指导教师：吴拥军，王威，路红显，王静，付晓丽.

会议报告

[1] 肺癌早期分子标志筛选与筛查模型的构建. 第十九次中国环境诱变剂学术大会（2023年，青岛），分会场报告

[2] 肺癌患者血浆外泌体蛋白质标志物筛选及其快速灵敏检测.全国生物标志物检测技术与研究学术论坛（2023年，武汉），大会报告

[3] 肺癌患者血浆外泌体分离及其蛋白质标志物同步检测体系的构建及应用. 第四届全国卫生检验与检疫专业学科建设与人才培养高层论坛（2022年，包头），大会报告