论文

[1]Ya Wang, Feng Yao, Lulu Song, Mengpan Zhang, Zitong Gong, Yunli Zhao, Yamin Xiong* and Leiliang He*. A supramolecular FRET signal amplification nanoprobe for high contrast and synchronous in situ imaging of cell surface receptor homodimers/heterodimers. Chemical Science, 2025, DOI: 10.1039/d4sc08004a. (中科院1区）

[2]Ya Wang, Yamin Xiong, Kangqi Shi, Clement Yaw Effah, Lulu Song, Leiliang He*, Jianbo Liu*. DNA nanostructures for exploring cell–cell communication. Chemical Society Reviews, 2024, DOI: 10.1039/d3cs00944k. (中科院1区）

[3]Lulu Song, Ya Wang, Yujing Guo, Shajidan Bulale, Miaomiao Zhou, Fei Yu*, Leiliang He*. Engineering aptamers to enhance their interaction with protein target for selective inhibition of cell surface receptors. International Journal of Biological Macromolecules, 2024, 278, 134989. (中科院1区）

[4]Ya Wang#, Yamin Xiong#, Yanjuan Duan, Kangqi Shi, Chaojie Su, Lihua Ding, Jia Wang, and Leiliang He*. Activatable fluorescence-encoded nanoprobes enable simple multiplexed RNA imaging in live cells. ACS Sensors, 2023, 8, 1918-1928.（中科院1区）

[5]Ya Wang, Yamin Xiong, Lulu Song, Sitian He, Feng Yao, Yongjun Wu, Kangqi Shi, and Leiliang He*. Spatial control of receptor dimerization using programmable DNA nanobridge. Biomacromolecules, 2023, 24, 3228-3236.（中科院1区）

[6]Leiliang He*, Kangqi Shi, Xinlian Liu, Ya Wang, Lulu Song, Di Wu, Yongjun Wu, Yamin Xiong, Peili Huang*. Engineering supramolecular ensemble for specific distinction of lung adenocarcinoma from inflammation. Sensors and Actuators: B. Chemical, 2023, 393, 134126. (中科院1区）

[7]Leiliang He, Jingjing Wang, Zhenzhen Wan, Yamin Xiong, Jin Man, Ya Wang, Guojiang Mao*, Fei Yu*. Biomimetic-compartmented nanoprobe for in-situ imaging of iron storage and release from ferritin in cells. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 286, 121967.（中科院2区）

[8]Ya Wang, Xinlian Liu, Longjie Wu, Lihua Ding, Clement Yaw Effah, Yongjun Wu, Yamin Xiong*, Leiliang He*. Construction and bioapplications of aptamer-based dual recognition strategy. Biosensors and Bioelectronics, 2022, 195,113661.（中科院1区）

[9]Xinlian Liu, Ya Wang, Clement Yaw Effah, Longjie Wu, Fei Yu, Jinlan Wei, Guojiang Mao, Yamin Xiong*, Leiliang He*. Endocytosis and intracellular RNAs imaging of nanomaterials-based fluorescence probes. Talanta, 2022, 243, 123377.（中科院1区）

[10]Lihua Ding, Yongjun Wu, Yanjuan Duan, Songcheng Yu, Fei Yu, Jia Wang, Yongmei Tian, Zibo Gao, Zhenzhen Wan, Leiliang He*. A novel cell-assisted enhanced chemiluminescence strategy for rapid and label-free detection of tumor cells in whole blood. ACS Sensors, 2020, 5, 440-446.（中科院1区）

[11]Leiliang He, Yanjuan Duan, Jiaodi Feng, Zhenzhen Wan, Xinlian Liu, Ya Wang, Fei Yu, Yilin Wang, Yamin Xiong*, Yongjun Wu*.  Apoferritin-based tunable nano-indicator for intracellular pH sensing: Regulating response performances and minimizing effects of system fluctuations. Sensors and Actuators: B. Chemical, 2020, 323, 128661.（中科院1区）

[12]Yamin Xiong, Lihong Zhou, Xiaoxia Peng, Huiling Li, Hui Wang, Leiliang He*, Peili Huang*. A specific short peptide-assisted enhanced chemiluminescence resonance energy transfer (CRET) for label-free and ratiometric detection of copper ions in complex samples. Sensors and Actuators: B. Chemical, 2020, 320, 128411.（中科院1区）

[13]Jiajia Dong#, Leiliang He#, Yilin Wang, Fei Yu, Songcheng Yu, Lie Liu, Jia Wang, Yongmei Tian, Lingbo Qu, Runping Han, Ziling Wang*, Yongjun Wu*. A highly sensitive colorimetric aptasensor for the detection of the vascular endothelial growth factor in human serum. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 226, 117622.（中科院2区）

[14]Leiliang He, Lihua Ding, Songcheng Yu, Fei Yu, Yongmei Tian, Xinsheng Xie, Lingbo Qu, Lie Liu*, Yongjun Wu*. Self-assembled poly-HRP dual signal amplification strategy for high-sensitive detection of circulating miR-142-3p in human serum. Sensors and Actuators: B. Chemical, 2019, 279, 440-446.（中科院1区）

[15]Lihua Ding, Yongjun Wu, Wei Liu, Lie Liu, Fei Yu, Songcheng Yu, Yongmei Tian, Jiaodi Feng, Leiliang He*. Magnetic-assisted self-assembled aptamer/protein hybrid probes for efficient capture and rapid detection of cancer cells in whole blood. Talanta, 2019, 205, 120129.（中科院1区）

[16]Yanhua Mao, Nana Wang, Fei Yu, Songcheng Yu, Lie Liu, Yongmei Tian, Jia Wang, Yilin Wang, Leiliang He*, Yongjun Wu*. Simultaneous detection of carcinoembryonic antigen and neuron-specific enolase in human serum based on time-resolved chemiluminescence immunoassay. Analyst, 2019, 144, 4813-4819.（中科院2区）

发明专利

[1]何磊良（1/9）; 一种用于细胞中铁蛋白储存和释放铁的检测方法, 2024-02-27, 中国, ZL 202110918246.7

[2]何磊良（1/9）; 激活式荧光编码铁蛋白纳米探针、制备及应用检测方法, 2023-06-20, 中国, ZL 202110918265.X

[3]何磊良（1/8）; 一种自组装聚HRP探针、制备方法、试剂盒及其应用, 2020-02-07, 中国, ZL 201710929595.2

[4]何磊良（1/9）; 一种自组装核酸适配体/蛋白质复合纳米探针、制备方法、试剂盒及其应用, 2021-04-06, 中国, ZL 201811357628.1

[5]何磊良（2/8）; 一种利用多种标志物联合检测外泌体的方法及试剂盒, 2023-08-08，中国，ZL 202110907130.3

[6]何磊良（3/9）; 靶向载体、靶向药物及靶向药物的应用、靶向探针及靶向探针的应用, 2019-03-29, 中国, ZL201610643160.7

[7]何磊良（1/6）; 一种混合超分子荧光纳米探针体系及其制备方法和应用, 2022-08-29, 中国, CN2022110389025

[8]何磊良（1/6）; 一种靶向调控细胞膜表面EGFR二聚化的DNA结构及其制备方法和应用, 2022-08-29, 中国, CN2022110389082

[9]何磊良（1/6）; 一种β-CD作为增强剂的PGM检测miR-21试剂盒及其应用, 2022-08-29, 中国, CN2022110390268

著作

[1]何磊良（副主编），卫生化学实验，郑州大学出版社, 2020

[2]何磊良（编委）. 食品中有害物质快速分析选论, 郑州大学出版社, 2019

其他

[1]2024年，指导本科生在第九届全国大学生生命科学竞赛（科学探究类）中获全国一等奖1项

[2]2022年，指导本科生获国家级大学生创新创业训练计划项目1项

[3]2019年，指导本科生在第十四届“挑战杯”河南省大学生课外学术科技作品竞赛中获省级三等奖1项