冯斐斐
冯斐斐 副教授,硕士生导师,卫生毒理学教研室副主任(主持工作),教工党支部书记,河南省优秀教学标兵,河南省高校青年骨干教师,河南省优秀硕士学位论文指导教师
研究方向:空气污染物、新污染物、气候等环境毒理学;化学物致癌机制与治疗;干细胞;营养素干预
联系电话:13838363115
邮箱:feifeifeng@zzu.edu.cn

论文

[1]Li M, Kong X, Jian X, Bo Y, Miao X, Chen H, Shang P, Zhou X, Wang L, Zhang Q, Deng Q, Xue Y*, Feng F*. Fatty acids metabolism in ozone-induced pulmonary inflammatory injury: Evidence, mechanism and prevention. Science of the Total Environment. 2024, 933: 173222.

[2]Wang W, Chang S, He X, Zhou X, Shang P, Chen Y, Wang X, Chen L, Zhang Q, Qiao Y*, Feng F*. Sulforaphane inhibits the migration and invasion of BPDE-induced lung adenocarcinoma cells by regulating NLRP12. Toxicology and Applied Pharmacology, 2024, 485:116916.

[3]Li M, Xue Y, Miao X, Ma P, Kong X, Jin Y, Li Y, Wang W, Zhang Q, Deng Q*, Feng F*. NLRP12 attenuates ozone-induced pulmonary inflammation by regulating canonical NF-κB Pathway. Ecotoxicology and Environmental Safety. 2023, 262:115275.

[4]Ma P, Miao X, Li M, Kong X, Jiang Y, Wang P, Zhang P, Shang P, Chen Y, Zhou X, Wang W, Zhang Q, Liu H, Feng F*. Lung proteomics combined with metabolomics reveals molecular characteristics of inflammation-related lung tumorigenesis induced by B(a)P and LPS. Environmental Toxicology. 2023, 38(12):2915-2925.

[5]Lei Y, Zhu Y, Mallah M, Lu P, Yang L, He X, Shang P, Chen Y, Zhou X, Feng F *, Zhang Q*. The activation of SIRT1 ameliorates BPDE-induced inflammatory damage in BEAS-2B cells via HMGB1/TLR4/NF-κB pathway. Environmental Toxicology. 2023, 38(10):2429-2439.

[6]Kong X, Gao M, Liu Y, Zhang P, Li M , Ma P, Shang P, Wang W, Liu H, Zhang Q, Feng F*.GSDMD-miR-223-NLRP3 axis involved in B(a)P-induced inflammatory injury of alveolar epithelial cells. Ecotoxicology and Environmental Safety. 2022, 232:113286.

[7]Zhang Q, He X, Yu Q, Liu Y, Zhu Y, Yang L, Shang P, Zhang J, Liu H, Feng F*. Endoplasmic reticulum stress regulates pyroptosis in BPDE-induced BEAS-2B cells. Environmental Toxicology. 2022, 37(7):1768-1780.

[8]Li M, Liu H, Shao H, Zhang P, Gao M, Huang L, Shang P, Zhang Q, Wang W, Feng F*. Glyburide attenuates B(a)p and LPS-induced inflammation-related lung tumorigenesis in mice. Environmental Toxicology. 2021, 36(8):1713-1722

[9]Shao H, Huang L, Duan S, Gao M, Zhu J, Chen X, Zhu Y, Wang W, Yang Z, Wang X, Wang Z, Wang Z, Ba Y, Zhang R, Li C, Zhang Q, Wang J, Liu H, Wu W, Feng F*. Glyburide attenuates ozone-induced pulmonary inflammation and injury by blocking the NLRP3 inflammasome. Environmental Toxicology.2020, 35(8):831-839.

[10]Li Z, Wang W, Meng L, Zhang Y, Zhang J, Li C, Wu Y, Feng F *, Zhang Q*. Identification and analysis of key lncRNAs in malignant-transformed BEAS-2B cells induced with coal tar pitch by microarray analysis.Environmental Toxicology and Pharmacology.2020, 79:103376.

[11]Gao M, Zhang P, Huang L, Shao H, Duan S, Li C, Zhang Q, Wang W, Wu Y, Wang J, Liu H, Feng F*. Is NLRP3 or NLRP6 inflammasome activation associated with inflammation-related lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide? Ecotoxicology and Environmental Safety. 2019, 185:109687.

[12]Duan S, Wang N, Huang L, Shao H, Zhang P, Wang W, Wu Y, Wang J, Liu H, Zhang Q, Feng F*.NLRP3 inflammasome activation involved in LPS and coal tar pitch extract-induced malignant transformation of human bronchial epithelial cells. Environmental Toxicology. 2019, 34(5):585-593.

[13]Huang L, Zhang P, Duan S, Shao H, Gao M, Zhang Q, Feng F*. The comparison of two mouse models of inflammation-related lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide. Experimental Animals. 2019, 68(3):301-306.

[14]Duan S, Wang N, Huang L, Zhao Y, Shao H, Jin Y, Zhang R, Li C, Wu W, Wang J, Feng F*. NLRP3 inflammasome activation is associated withPM2.5-induced cardiac functional and pathologicalinjury in mice. Environmental Toxicology. 2019, 34(11):1246-1254.

[15]Li Z, Zhang Y, Meng L, Yang S, Zhang P, Zhang J, Li C, Feng F *, Zhang Q*. LncRNA-ENST00000501520 promotes the proliferation of malignant-transformed BEAS-2B cells induced with coal tar pitch mediated by target genes. Environmental Toxicology. 2019, 34(7):869-877.

[16]Huang L, Duan S, Shao H, Zhang A, Chen S, Zhang P, Wang N, Wang W, Wu Y, Wang J, Liu H, Yao W, Zhang Q, Feng F*. NLRP3 deletion inhibits inflammation-driven mouse lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide. Respiratory Research. 2019, 20(1):20.

著作

[1]冯斐斐(参编),臭氧污染与健康. 湖北科学技术出版社,2021

会议报告

[1]2023年中国毒理学会呼吸毒理专委会学术会议,大会报告,陕西西安,2023.05

[2]第九届亚洲毒理学国际大会“呼吸毒理”分会场报告,中国浙江杭州,2021.10

[3]第6届亚洲环境诱变剂学会(ACEM)国际会议,壁报,Tokyo,Japan,2019.11

[4]2018年美国胸科学会国际会议,壁报,San Diego, USA, 2018.05

发明专利

[1] 冯斐斐(第一完成人),快速吸入式气管滴注给药系统. ZL 2015 1 0048160.8,2017.02

奖励

[1]冯斐斐(3/5),空气污染物对呼吸道和心血管系统的毒性作用及其机制,河南省人民政府,河南省自然科学奖,三等奖,2021

[2]冯斐斐(5/10),煤焦沥青致支气管上皮细胞染色体不稳定性研究,河南省人民政府,河南省科技进步奖,二等奖,2014