1. 基本介绍

付凯玉，博士，现任公共卫生学院副研究员， 在Environmental Science & Technology、 Journal of Hazardous Materials等期刊发表学术论文十余篇。研究领域为环境毒理学。主要研究方向为 （1）评估新污染物对肝脏代谢、生殖系统的毒性效应，阐明其传代/跨代健康影响及分子作用机制，为新污染物对生态环境与人类健康的潜在风险提供数据支持。（2）针对代表性水体、土壤中多种污染物开展周期性监测，获取典型污染物暴露水平、空间分布以及季节分布特征。通过多层次风险评价方法评估其对水生态系统和人类健康的潜在风险，为生态保护和环境管理政策的制定提供科学依据。

2. 教育工作经历

工作经历：

2025.9-至今，郑州大学，公共卫生学院，环境卫生教研室，副研究员。

教育经历：

2020.9-2025.6，中国科学院水生生物研究所，水生生物学，硕博连读。

2016.9-2020.6，河南师范大学，水产学院，水族科学与技术，本科。

3. 学术荣誉/兼职

中国科学院院长奖学金

博士研究生国家奖学金

第十三届全国环境化学大会，环境化学优秀奖

中国环境科学学会气候与健康分会委员

4. 主持/参与科研项目

[1] 新溴代阻燃剂诱导代谢紊乱致斑马鱼生殖障碍的机制研究，2026-2028，主持

[2] 国家自然科学基金面上项目“新型溴代阻燃剂对中枢神经系统的内暴露、毒性效应及分子机制研究”，2022- 2025，参与

5. 代表性成果

论文

[1] Kaiyu Fu; Biran Zhu; Yumiao Sun; Yuxi Zhou; Hao Pang; Xinxin Ren; Yongyong Guo; Xiongjie Shi; Jian Han; Lihua Yang; Bingsheng Zhou, 2024. Bis (2-ethylhexyl)-tetrabromophthalate poses a higher exposure risk and induces gender-specific metabolic disruptions in zebrafish liver. Environmental Science & Technology, 58(11):4937-4947. （中科院一区Top期刊，IF=12.2）

[2] Kaiyu Fu#; Jianghuan Hua#; Yindan Zhang; Mingpu Du; Jian Han; Na Li; Qiangwei Wang; Lihua Yang; Ruiwen Li; Bingsheng Zhou, 2024. Integrated studies on male reproductive toxicity of bis(2-ethylhexyl)-tetrabromophthalate: in Silico, in Vitro, ex Vivo, and in Vivo. Environmental Science & Technology, 58(1):194-206.（中科院一区Top期刊，IF=12.2）

[3] Xiaochen Wang; Kaiyu Fu*; Jianghuan Hua; Mingyang Li; Lingzhi Tan; Lihua Yang; Jian Han;Weimin Xie; Bingsheng Zhou; Tissue uptake, Distribution, Elimination and Neurotoxicity of Decabromodiphenyl ethane (DBDPE) in Adult Zebrafish (Danio Rerio), Aquatic Toxicology, 2026, 291:107705. （中科院二区期刊，IF=4.6）

[4]  Yuxi Zhou; Kaiyu Fu; Fan Li; Yindan Zhang; Xinxin Ren; Bingjie Li; Shengmin Wu; Jian Han; Lihua Yang; Bingsheng Zhou, 2024. UV-aging process of titanium dioxide nanoparticles aggravates enterohepatic toxicity of bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate to zebrafish. The Science of the total environment, 958:178074.（中科院二区期刊，IF=8）

[5]  Yuxi Zhou; Fan Li; Kaiyu Fu; Yindan Zhang; Na Zheng; Huijia Tang; Zhixiang Xu; Lijun Luo; Jian Han; Lihua Yang; Bingsheng Zhou, 2024. Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate Enhances foxo1-Mediated Lipophagy to Remodel Lipid Metabolism in Zebrafish Liver. Environmental Science & Technology, 58(10):4581-4593.（中科院一区Top期刊，IF=12.2）

[6] Yan Biao; Sun Yumiao; Fu Kaiyu; Zhang Yindan; Lei Lei; Men Jun; Guo Yongyong; Wu Shengmin; Han Jian; Zhou Bingsheng. 2023. Effects of glyphosate exposure on gut-liver axis:Metabolomic and mechanistic analysis in grass carp (Ctenopharyngodon idellus). The Science of the total environment, 902:166062.（中科院二区期刊，IF=8）

[7] Zhu Biran#; Lei Lei#; Fu Kaiyu; Zhao Songlin; Hua Jianghuan; Yang Lihua; Han Jian; Li Rui; Zhou Bingsheng. 2022. Neurotoxicity of tetrabromobisphenol A and SiO2 nanoparticle co-exposure in zebrafish and barrier function of the embryonic chorion. The Science of the total environment, 845:157364. （中科院二区期刊，IF=8）

[8] Xue Hu; Shengmin Wu; Ruiwen Li; Chengqian Liang; Kaiyu Fu; Fan Li; Yindan Zhang; Yumiao Sun; Lihua Yang; Yongyong Guo; Xiaochen Wang; Jian Han; Weimin Xie; Bingsheng Zhou; Pesticide pollution in the Yangtze River mainstem under extreme drought climate: Occurrences, risks and linkages to land use, Environmental Chemistry and Ecotoxicology, 2026, 8:1967-1983.（中科院一区期刊，IF=12.3）

[9] Zhu Biran; Chen Xianglin; Zhang Taotao; Zhang Qianqian; Fu Kaiyu; Hua Jianghuan; Zhang Mengyuan; Qi Qing; Zhao Binbin; Zhao Min; Yang Lihua; Zhou Bingsheng. 2024. Interactions between intestinal microbiota and metabolites in zebrafish larvae exposed to polystyrene nanoplastics: Implications for intestinal health and glycolipid metabolism. Journal of Hazardous Materials, 472:134478. （中科院一区期刊，IF=10.6）

[10] Sun Yumiao; Zhou Shanqi; Zhu Biran; Li Fan; Fu Kaiyu; Guo Yongyong; Men Jun; Han Jian; Zhang Wei; Yang Lihua;Zhou Bingsheng. 2023. Multi- and Transgenerational Developmental Impairments Are Induced by Decabromodiphenyl Ethane (DBDPE) in Zebrafish Larvae. Environmental Science and Technology, 57(7):2887-2897.（中科院一区Top期刊，IF=12.2）

[11] Zhu Biran; Lei Lei; Sun Yumiao; Shi Xiongjie; Fu Kaiyu; Hua Jianghuan; Martyniuk Christopher J; Han Jian; Yang Lihua; Zhou Bingsheng. 2022. Niclosamide Exposure at Environmentally Relevant Concentrations Efficaciously Inhibited the Growth and Disturbed the Liver-Gut Axis of Adult Male Zebrafish. Environmental Science and Technology, 56(16):11516-11526. （中科院一区Top期刊，IF=12.2）

[12] Jianghuan Hua; Taotao Zhang; Xianglin Chen; Biran Zhu; Min Zhao; Yindan Zhang; Huijia Tang; Hao Pang; Yongyong Guo; Jian Han; Lihua Yang; Bingsheng Zhou. 2024. Behavioral impairments and disrupted mitochondrial energy metabolism induced by polypropylene microplastics in zebrafish larvae. The Science of the total environment, 947, 174541.（中科院二区期刊，IF=8）