基本介绍

玉崧成，男，1983年生，中共党员，博士，教授，硕士生导师，卫生化学教研室副主任，郑州大学青年骨干教师，中国营养学会营养与组学技术分会常务委员，长期从事高通量快速检测技术在食品安全及营养相关疾病中的应用研究，主持和参与国家自然科学基金4项，主持河南省自然科学基金1项，主持河南省重点研发与推广专项（科技攻关）项目1项，以第一发明人获得国家授权发明专利4项，以第一作者或通讯作者在ACS Sensors、Biosensors and Bioelectronics、ACS Synthetic Biology、Small Methods、Talanta、Analytica Chimica Acta、Food Control、Nutrition、Nutrition Research、Journal of Diabetes、Journal of Diabetes and its Complications等国际学术期刊发表SCI收录论文30余篇。

教育工作经历

工作经历：

[1]2025-至今， 郑州大学公共卫生学院，教授

[2]2019-2024，郑州大学公共卫生学院，副教授

[3]2013-2019，郑州大学公共卫生学院，讲师

[4]2009-2012，郑州大学公共卫生学院，助教

[5]2008-2009，深圳迈瑞生物医疗电子股份有限公司，工程师

教育经历：

[1]2014-2018，郑州大学，营养与食品卫生学专业，博士

[2]2005-2008，吉林大学，生物化学与分子生物学专业，硕士

[3]2001-2005，吉林大学，生物科学，本科

学术荣誉/兼职

[1]中国营养学会营养与组学技术分会委员

主持科研项目

[1]国家自然科学基金青年项目（编号：81703270；年限：2018-2020）：基于单分子免疫阵列的DNA甲基化关键分子5mC和5hmC超灵敏同步分析新方法的构建与评价

[2]河南省重点研发与推广专项（科技攻关）项目（编号：192102210037；年限：2019-2020）：DNA甲基化和去甲基化同步检测试剂盒的研发

论文

[1]Lihua Ding, Shengnan Cao, Lanxin Bai, Sitian He, Leiliang He, Yilin Wang, Yongjun Wu, Songcheng Yu*. Versatile Fluorescence Biosensors Based on CRISPR/Cas12a for Determination of Site-Specific DNA Methylation from Blood and Tissues. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2025, 329: 125520.

[2]Xueying Lei, Lihua Ding, Xiaonan Yang, Feng Xu, Yongjun Wu, Songcheng Yu*. PAIT effect: Padlock activator inhibits the trans-cleavage activity of CRISPR/Cas12a. Biosensors and Bioelectronics, 2024, 263: 116607.

[3]Lihua Ding, Shengnan Cao, Chenling Qu, Yongjun Wu, Songcheng Yu*. Ratiometric CRISPR/Cas12a-Triggered CHA System Coupling with the MSRE to Detect Site-Specific DNA Methylation. ACS Sensors, 2024, 9(4): 1877-1885.

[4]Xueying Lei, Shengnan Cao, Tao Liu, Yongjun Wu, Songcheng Yu*. Non-canonical CRISPR/Cas12a-based technology: A novel horizon for biosensing in nucleic acid detection. Talanta, 2024, 271: 125663.

[5]Cong Wei, Xueying Lei, Songcheng Yu*. Multiplexed Detection Strategies for Biosensors Based on the CRISPR-Cas System. ACS Synthetic Biology, 2024, 13 (6): 1633–1646.

[6]Songcheng Yu*, Xueying Lei, Chenling Qu*. MicroRNA Sensors Based on CRISPR/Cas12a Technologies: Evolution from Indirect to Direct Detection. Critical Review in Analytical Chemistry, 2024, DOI: 10.1080/10408347.2024.2329229

[7]Songcheng Yu, Shengnan Cao, Sitian He, Kaixiang Zhang. Locus‐Specific Detection of DNA Methylation: The Advance, Challenge, and Perspective of CRISPR‐Cas Assisted Biosensors. Small Methods, 2023, 7(2): e2201624.

[8]Bingqian Wang, Jian Hou, Zhenxing Mao, Changying Chen, Chongjian Wang, Songcheng Yu*. Association between Dinner-bedtime interval and type 2 diabetes mellitus: a large-scale cross-sectional study. Journal of Diabetes & Metabolic Disorders, 2024, 23(1):1039-1045.

[9]Kaiyang Zhang, Yinhua Feng, Yuanyuan Chai, Chongjian Wang, Songcheng Yu*. The association between dinner timing and glucose metabolism in rural China: a large-scale cross-sectional study. Nutrition, 2023, 112158

[10]Hongyun Chen, Yinhua Feng, Changying Chen, Songcheng Yu*. Both early and late maternal age at childbirth is associated with increasing odds of central obesity in offspring. American Journal of Human Biology, 2023, e2389.

[11]Sitian He, Songcheng Yu*, Yinhua Feng, Leiliang He, Lie Liu, Clement Yaw Effah, Yongjun Wu*. A digital immuno-PCR assay for simultaneous determination of 5-methylcytosine and 5-hydroxymethylcytosine in human serum. Analytica Chimica Acta, 2022, 1192: 339321.

[12]Songcheng Yu, Yinhua Feng, Chenling Qu, Fei Yu, Zhenxing Mao, Chongjian Wang, Wenjie Li, Xing Li*. Vitamin D receptor methylation attenuates the association between physical activity and type 2 diabetes mellitus: A case-control study. Journal of Diabetes, 2022, 14(2): 97-103

[13]Lanxin Bai, Chenling Qu, Yinhua Feng, Gangqiong Liu, Xing Li, Wenjie Li, Songcheng Yu*. Evidence of a casual relationship between vitamin D deficiency and hypertension: a family-based study. Hypertension Research, 2022, 45(11): 1814-1822.

[14]Yuanyuan Chai, Chenling Qu, Zhenxing Mao, Chongjian Wang, Songcheng Yu*. Sex differences in the association between dinner–bedtime interval and abdominal obesity: a large‑scale cross‑sectional study. Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity, 2022, 27(8):3479-3486.

专利

[1]玉崧成, 吴拥军, 合思甜, 何磊良, 付晓丽, 曾鑫, 董佳佳, 杨军辉, 候一心, 丁帅. 一种可视化全自动偶联反应装置. 2020.7.30，专利号：ZL2018114705608

[2]玉崧成, 吴拥军, 合思甜, 于斐, 刘利娥, 田咏梅, 王佳, 王艺琳, 王华栋, 吴予明, 刘洁. 一种可视化偶联反应试剂盒. 2021.2.2，专利号：ZL 2018114705595

教材

[1]玉崧成（主编），《卫生化学实验》，2020年，郑州大学出版社