基本介绍

赵有亮，男，1995年生，博士学历，直聘副研究员。主要研究方向为矽肺发病的免疫调控机制。

教育工作经历

工作经历：

[1]2024-至今，郑州大学，公共卫生学院，直聘副研究员

教育经历：

[1]2020-2024，郑州大学，公共卫生学院，劳动卫生与环境卫生学专业，博士

[2]2017-2020，郑州大学，公共卫生学院，公共卫生，硕士

[3]2013-2017，湖北中医药大学，检验学院，卫生检验与检疫，学士.

学术荣誉/兼职

学术兼职

2024年12月，中国毒理学会免疫毒理专业委员会，青年委员

主持科研项目

暂无

论文

[1]Zhao, Y., Qu, Y., Duan, M., Qi, Y., Xia, J., Hao, C., & Yao, W. (2025). PD-L1 upregulation in activated fibroblasts promotes silica particle-induced pulmonary fibrosis. International journal of biological macromolecules, 291, 139147.

[2]Zhao, Y., Qi, Y., Duan, M., Hao, C., & Yao, W. (2024). Time-series transcriptome analysis mapping pulmonary immune checkpoint atlas of experimental silicosis. Genes & diseases, 12(1), 101258.

[3]Zhao, Y., Qi, Y., Xia, J., Duan, M., Hao, C., & Yao, W. (2024). The role of the PI3K/AKT/mTOR pathway in mediating PD-L1 upregulation during fibroblast transdifferentiation. International immunopharmacology, 142(Pt B), 113186.

[4]Zhao, Y., Qu, Y., Duan, M., Hao, C., & Yao, W. (2023). Dynamics of the inhibitory immune checkpoint TIM-3 in mouse pulmonary phagocytes after silica exposure. Ecotoxicology and environmental safety, 261, 115087.

[5]Zhao, Y., Qu, Y., Hao, C., & Yao, W. (2023). PD-1/PD-L1 axis in organ fibrosis. Frontiers in immunology, 14, 1145682.

[6]Zhao, Y., Hao, C., Li, M., Qu, Y., Guo, Y., Deng, X., Si, H., & Yao, W. (2022). PD-1/PD-L1 inhibitor ameliorates silica-induced pulmonary fibrosis by maintaining systemic immune homeostasis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 148, 112768.

[7]Zhao, Y., Hao, C., Bao, L., Wang, D., Li, Y., Qu, Y., Ding, M., Zhao, A., & Yao, W. (2020). Silica particles disorganize the polarization of pulmonary macrophages in mice. Ecotoxicology and environmental safety, 193, 110364.

[8]Zhao, Y., Hao, C., Zhai, R., Bao, L., Wang, D., Li, Y., Yu, X., Huang, R., & Yao, W. (2019). Effects of cyclophosphamide on the phenotypes and functions of THP-1 cells. Environmental toxicology and pharmacology, 70, 103201.

会议报告

[1]PD-1/PD-L1促进实验性矽肺发生发展的作用与调控机制. 2024年肿瘤防控与免疫调节促进高质量发展学术会议（2024年，郑州），分会场报告