基本介绍

余增丽，女，1970年生，教授，博士生导师，学科方向带头人，营养与食品卫生学教研室主任，营养相关疾病团队负责人。获“教育部新世纪优秀人才”、“中原科技创新领军人才”、“郑州市十大科技女杰”、“河南省科技创新杰出青年”、“河南省学术技术带头人”、“河南省高校科技创新人才”等荣誉。主持并完成4项国家自然科学基金及20余项省部级科研项目，发表学术论文100余篇，包括Environ Res, Environ Pollut, Ecotoxicol Environ Saf, Environ Int, Neurology及Front Immunol等国际知名期刊，出版专著1部，译著1部，参编教材4部，获河南省科技进步二等奖2项。

教育及工作经历

2008.6- 现在  郑州大学公共卫生学院，教授

2005.6-2008.5    美国Duke University，访问学者

2003.7-2005.5    北京大学，营养与食品卫生学专业，博士后

2000.9-2003.6    四川大学，营养与食品卫生学专业，博士

1997.9-2000.6    河南医科大学，营养与食品卫生学专业，硕士

1988.9-1993.6    河南医科大学，医学学士

学术荣誉/兼职

学术荣誉

2009年度，教育部新世纪优秀人才

2020年度，中原科技创新领军人才

2023年度，郑州市十大科技女杰

2013年度，河南省学术技术带头人

2014年度，河南省科技创新杰出青年

2005年度，河南省高校科技创新人才

学术兼职

[1]香港中文大学讲座教授

[2]中国营养学会肥胖防控分会，委员

[3]河南省临床营养师协会，副主任委员

[4]中国学生营养与健康促进会河南代表处，副主任

[5]河南省妇幼健康协会，副主任委员

主持科研项目

[1] 多组学联合机器学习算法探究新污染物致子代孤独症谱系障碍的机制及干预策略. 河南省科技厅重点研发251111314800，120万元，负责人

[2] MEG3在二噁英经维生素A途径诱发腭裂的作用机制. 中原科技创新领军人才No.214200510016，100万元，负责人

[3] 河南省围产期疾病健康管理及防控体系构建. 河南省重大公益专项No. 201300310800，250万元，子课题负责人

[4] 二噁英和维生素A在腭裂诱发中的相互作用及机制. 国家自然科学基金面上项目No.21577119. 68万元，负责人

[5] 维生素A在二噁英诱发出生缺陷中的作用及机制. 国家自然科学基金项目No.81370779. 负责人

[6] VitA和TGFβ在腭裂诱发中的相互作用及机制.国家自然科学基金面上项目NO.81170630. 65万元，负责人

[7] 诱发腭裂的风险因素及预防措施的研究，教育部新世纪优秀人才支持计划NCET-09-0123，50万元，负责人

[8] 不良妊娠结局风险因素筛查及预警体系的建立. 河南省科技创新杰出青年基金No.134100510014，30万元，负责人

[9] 膳食因素在腭裂诱发中的作用及机制. 河南省教育厅基础研究专项20ZX012，30万元，负责人

[10] 基于肠道微生态肥胖儿童干预策略研究. 中国营养学会，20万元，负责人

代表性论文

[1] Gong Y, Li Z, Yao Q, Zhi M, Zhang X, Zhang J, Yu Z*, Zhao X*. Air pollution and maternal vitamin D Status: Critical time window identification and ultraviolet radiation-mediated pathways. Int J Hyg Environ Health. 2025 Aug;269:114648.

[2] Wu SY, Bo YC, Li ZY, Hu XY, Ning YY, Huang J, Zhang JX, Zhu YJ, Yu Z*, Liu HY. EAT-Lancet diet and risk of metabolic dysfunction-associated steatotic liver disease and other liver chronic diseases: a large prospective cohort study in the UK Biobank. Front Nutr. 2025 Jul 31;12:1589424.

[3] Gao P, Ji X, Wang W, Chen Y, Gao Z, Yu Z*. Association between coffee and caffeine consumption and chronic kidney disease. Sci Rep. 2025 Jul 12;15(1):25228.

[4] Yu Z#, Su H, Gao Z, Chen Y, Zhang Y, Duan W, Zhang T, Wang X, Xu D, Liu X. Meg3-NONO-RAR axis mediates RA pathway activation in TCDD-induced cleft palate. Toxicology. 2025 Jun;514:154099.

[5] Bo Y, Sun L, Hou S, Zhang F, Zhang H, Feng X, Zhuo S, Feng S, Chang H, Zhang X, Wang Z, Yu Z*, Zhao X. Associations of Accelerated Biological Aging With Dementia and the Mediation Role of Brain Structure: Findings From a Longitudinal Study. Neurology. 2025 May 27;104(10):e213616.

[6] Zhang H, Zhou J, Cao Y, Zhang X, Chang H, Zhao Y, Bo Y, Zhang H, Yu Z*, Zhao X. Association between telomere length and psychiatric disorders: a bidirectional Mendelian randomization study. Eur Arch Psychiatry Clin Neurosci. 2025 Apr 25.

[7] Yu Z#, Zhang Y, Wu S, Sun Z, Gao Z, Chen Y, Wang X, Xu D, Liu X. The mediating mechanism of Oct4 in the process of cleft palate induced by 2, 3, 7, 8-tetrachlorodibenz-p-dioxin (TCDD) and all-trans retinoic acid. Ecotoxicol Environ Saf. 2025 Apr 15;295:118102.

[8] Yu Z#, Zhang Y, Wang G, Song S, Su H, Wu Y, Zhang Y, Liu P, Liu X. The mechanism of all-trans retinoic acid-induced cleft palate may be related to the novel ENSMUST00000159153-miR-137-5p-Wnt7a and ENSMUST000000236086-miR-34b-3p-EphA10/TRPM2 ceRNA crosstalk. Environ Toxicol Pharmacol. 2025 Mar;114:104623.

[9] Khatoon N, Ali S, Hussain A, Huang J, Li Z, Yu Z*, Liu H. Human health risks of heavy metals in water and vegetables: a deterministic and probabilistic study in Gilgit-Baltistan, Pakistan. Environ Geochem Health. 2025 Feb 25;47(3):88.

[10] Khatoon N, Ali S, Hussain A, Huang J, Yu Z*, Liu H. Evaluating the Carcinogenic and Non-Carcinogenic Health Risks of Heavy Metals Contamination in Drinking Water, Vegetables, and Soil from Gilgit-Baltistan, Pakistan. Toxics. 2024 Dec 25;13(1):5.

[11] Yu Z#, Zhang Y, Wang G, Song S, Su H, Duan W, Wu Y, Zhang Y, Liu X. Identification of competing endogenous RNA networks associated with circRNA and lncRNA in TCDD-induced cleft palate development. Toxicol Lett. 2024 Nov;401:71-81.

[12] Liu X, Song S, Wang G, Zhang Y, Su H, Wu Y, Zhang Y, Liu H, Wang X, Yu Z*. Upregulated LncRNA-Meg3 modulates the proliferation and survival of MEPM cells via interacting with Smad signaling in TCDD-induced cleft palate. Food Chem Toxicol. 2024 Mar;185:114410.

[13] Yu Z#, Liu H, Liu X, Tao Y, Zhang X, Zhao X, Chang H, Huang J, Zhao Y, Zhang H, Huang C. Correction to: Dynamic changes in ambient PM2.5 and body mass index among old adults: a nationwide cohort study. Environ Sci Pollut Res Int. 2024 Feb;31(10):16107.

[14] Zhang H, Zhang X, Feng D, Gao Z, Gong Y, Zhang J, Song S, Yu Z*, Huang C. Interaction effects of night-time temperature and PM2.5 on preterm birth in Huai River Basin, China. Environ Int. 2023 Jan;171:107729.

[15] Zhang H, Zhang X, Zhang H, Luo H, Feng Y, Wang J, Huang C, Yu Z*. Assessing the effect of fine particulate matter on adverse birth outcomes in Huai River Basin, Henan, China, 2013-2018. Environ Pollut. 2022 Aug 1;306:119357.

[16] Bo Y, Zhu Y, Zhang X, Chang H, Zhang J, Lao XQ, Yu Z*. Spatiotemporal Trends of Stroke Burden Attributable to Ambient PM2.5 in 204 Countries and Territories, 1990-2019: A Global Analysis. Neurology. 2023 Aug 15;101(7):e764-e776.

[17] Ding D, Wang B, Zhang X, Zhang J, Zhang H, Liu X, Gao Z, Yu Z*. The spread of antibiotic resistance to humans and potential protection strategies. Ecotoxicol Environ Saf. 2023 Apr 1;254:114734.

[18] Yu Z#, Song S, Wang G, Zhang Y, Zhang Y, Wu Y, Liu H, Zhang Y, Liu X. The mechanisms governing mouse embryonic palate mesenchymal cells' proliferation associated with atRA-induced cleft palate in mice: insights from integrated transcriptomic and metabolomic analyses. Arch Toxicol. 2023 Aug;97(8):2143-2153.

[19] Su H, Bo Y, Zhang X, Zhang J, Gao Z, Yu Z*. Associations of folate intake with all-cause and cause-specific mortality among individuals with diabetes. Front Nutr. 2022 Oct 14;9:1021709.

[20] Wang B, Ding D, Zhang X, Zhang J, Zhang H, Liu X, Chang H, Gao Z, Yu Z*. The Role of Protein Arginine Methyltransferases in Pathogenesis and Treatment of Digestive System Carcinoma. Mol Cancer Ther. 2023 Aug 1;22(8):926-935.

[21] Yu Z#, Zhao D, Liu X. Nutritional supplements improve cardiovascular risk factors in overweight and obese patients: A Bayesian network meta-analysis. Front Nutr. 2023 Mar 30;10:1140019.

[22] Yu Z#, Liu H, Liu X, Tao Y, Zhang X, Zhao X, Chang H, Huang J, Zhao Y, Zhang H, Huang C. Dynamic changes in ambient PM2.5 and body mass index among old adults: a nationwide cohort study. Environ Sci Pollut Res Int. 2023 Oct 28. 1

[23] Yu Z#, Wang G, Song S, Zhang Y, Wu Y, Zhang Y, Duan W, Liu X. Associations between the proliferation of palatal mesenchymal cells, Tgfβ2 promoter methylation, Meg3 expression, and Smad signaling in atRA-induced cleft palate. Reprod Toxicol. 2023 Oct 20;122:108486.

[24] Gong Y, Zhang X, Zhao X, Chang H, Zhang J, Gao Z, Mi Y, Chen Y, Zhang H*, Huang C, Yu Z*. Global ambient particulate matter pollution and neurodegenerative disorders: a systematic review of literature and meta-analysis. Environ Sci Pollut Res Int. 2023 Mar;30(14):39418-39430.

[25] Zhang H #, Zhang X, Zhao X, Cheng G, Chang H, Ye X, Wang J, Yu Z*, Wang Q, Huang C. Maternal exposure to air pollution and congenital heart diseases in Henan, China: A register-based case-control study. Ecotoxicol Environ Saf. 2022 Jan 1; 229:113070.

[26] Yu Z#, Zhang X, Zhang J, Feng Y, Zhang H, Wan Z, Xiao C, Zhang H, Wang Q, Huang C. Gestational exposure to ambient particulate matter and preterm birth: An updated systematic review and meta-analysis. Environ Res. 2022 Sep;212(Pt C):113381.

[27] Bo Y #, Xu H, Zhang H, Zhang J, Wan Z, Zhao X, Yu Z*. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort. Nutrients. 2022 May 27;14(11):2253.

[28] Zhang H #, Zhang X, Wang Q, Xu Y, Feng Y, Yu Z*, Huang Cunrui. Ambient air pollution and stillbirth: An updated systematic review and meta-analysis of epidemiological studies. Environ Pollut. 2021, 278:116752.