1.基本信息赵阳，女，1989年出生。博士，讲师。主要研究方向为心血管代谢异常的传统及遗传流行病学研究。
2.教育经历
2018-02至2019-10,杜兰大学,公共卫生学院,博士联合培养,导师:Jiang He
2014-09至2020-07,郑州大学,公共卫生学院,博士,导师:胡东生
2007-09至2012-07,郑州大学,临床医学系,学士
3.科研与学术工作经历
2020-07至现在,郑州大学,公共卫生学院,讲师
2020-08至现在,郑州大学,药学院,博士后,导师:张振中
4.主持或参加科研项目（课题）情况
郑州大学求是教师科研启动金，不同代谢特征与脑卒中关系的队列研究，2020-07至2022-07，20万元，在研，主持
国家自然科学基金，面上项目，81973152，基于移动健康技术干预动脉粥样硬化性心血管疾病高危人群的随机对照现场试验：The ASCVD Risk Intervention Trial，2020-01至2023-12，54万元，在研，参与
国家自然科学基金，面上项目，81673260，DNA甲基化水平及动态变化与2型糖尿病关联的前瞻性巢式病例对照研究，2017-01至2020-12，65万元，在研，参与
5.对个人研究领域的描述
肥胖是众多慢性非传染性疾病（如糖尿病，高血压，脑卒中等）的危险因素。肥胖人群因其体内脂肪过度蓄积常伴有胰岛素抵抗、血脂异常等代谢异常特征，被称为代谢异常肥胖。在全球20岁及以上成人中，约35%的肥胖人群表现为良好的代谢状态，即“代谢健康肥胖（Metabolically healthy obesity，MHO）”表型。MHO表型与人群健康的关系仍不完全清楚，且与心血管疾病发病风险的研究结论尚不一致。目前，基于西方人群有关MHO患病情况及其与心血管疾病和糖尿病发病关系的研究报道较多，缺乏有关中国人群的研究。同时，既往研究的结论并不完全一致，且存在代谢健康的诊断标准不统一及忽略腹型肥胖类型等问题。此外，人体的肥胖和代谢状态会随着年龄的增长及生活方式的改变而发生变化，有关肥胖和代谢状态的动态变化转归及其与心血管疾病发病风险的研究证据十分有限。2014年，中国成人肥胖人数居世界首位。中国农村地区肥胖和心血管疾病患病率呈上升趋势。我国农村人群MHO表型患病情况如何？MHO是否增加心血管疾病发病的风险？不同代谢特征人群长期的肥胖和代谢特征动态变化水平是否影响心血管疾病的发病？基因以及外环境危险因素如何影响MHO与心血管疾病发生的关系？这些科学问题至今未被研究。基于以上研究背景，本课题组采用前瞻性队列研究设计，选择河南农村地区成年人群为研究对象，通过建立基线研究以及开展多次长期随访调查，旨在从代谢的角度深入探索肥胖和人群健康的潜在关联。本课题的研究结果将有助于科学制定基于河南农村人群的心血管疾病预防控制策略，缓解心血管疾病的防治压力，同时为今后针对我国农村人群心血管疾病防治干预项目的开展提供前瞻性的科学依据。
6.代表性研究成果
期刊论文
(1)Pei Qin#,Quanman Li#,Yang Zhao#,Qing Chen,Xizhuo Sun,Yu Liu,Honghui Li,Tieqiang Wang,Xiaoliang Chen,Qionggui Zhou,Chunmei Guo,Dongdong Zhang,Gang Tian,Dechen Liu,Ranran Qie,Minghui Han,Shengbing Huang,Xiaoyan Wu,Yang Li,Yifei Feng,Xingjin Yang,Fulan Hu,Dongsheng Hu, andMing Zhang*.Sugar and artificially sweetened beverages and risk of obesity,type 2 diabetes mellitus, hypertension, and all‑cause mortality:a dose–response meta‑analysis of prospective cohort studies. European Journal of Epidemiology. 2020; 35(7):655-671.
(2)Yang Zhao#, Pei Qin#, Haohang Sun, Yu Liu, Dechen Liu, Qionggui Zhou, Chunmei Guo, Quanman Li, Gang Tian, Xiaoyan Wu, Dongsheng Hu, Xizhuo Sun, and Ming Zhang*. Metabolically healthy general and abdominal obesity are associated with increased risk of hypertension. British Journal of Nutrition.2020;123(5):583-591.
(3)Yang Zhao, Qin Pei, Haohang Sun, Zhaoxia Yin, Honghui Li, Xizhuo Sun, Feiyan Liu, Yongcheng Ren, Dechen Liu, Xu Chen, Leilei Liu, Cheng Cheng, Qionggui Zhou, Ming Zhang, Yu Liu*, and Dongsheng Hu*. Resting heart rate and its dynamic change and the risk of hypertension: The Rural Chinese Cohort Study. Journal of Human Hypertension.2020;34(7):528-535.
(4)Yang Zhao, Ming Zhang, Yu Liu, Haohang Sun, Xizhuo Sun, Zhaoxia Yin, Honghui Li, Yongcheng Ren, Dechen Liu, Feiyan Liu, Xu Chen, Leilei Liu, Cheng Cheng, Qionggui Zhou, and Dongsheng Hu*. Adult height and risk of death from all-cause, cardiovascular and cancer specific disease: The Rural Chinese Cohort Study. Nutrition, Metabolism, and Cardiovascular disease.2019; 29(12):1299-1307.
(5)Yang Zhao, Ming Zhang, Yu Liu, Zhaoxia Yin, Honghui Li, Haohang Sun, Chongjian Wang, Yongcheng Ren, Dechen Liu, Cheng Cheng, Feiyan Liu, Xu Chen, Leilei Liu, Qionggui Zhou, Yihan Xiong, Qihuan Xu, Jiali Liu, Shihao Hong, Ziyang You, Jianxin Li, Jie Cao, Jianfeng Huang, Xizhuo Sun, and Dongsheng Hu*. 6-year change in resting heart rate is associated with incident type 2 diabetes mellitus. Nutrition, Metabolism, and Cardiovascular disease.2019; 29(3):236-243.
(6)Yang Zhao, Yu Liu, Haohang Sun, Xizhuo Sun, Yinzhao Xia, Honghui Li, Yongcheng Ren, Bingyuan Wang, Dongdong Zhang, Xuejiao Liu, Ruiyuan Zhang, Feiyan Liu, Cheng Cheng, Qionggui Zhou, Dongsheng Hu, and Ming Zhang*. Body mass index and risk of all-cause mortality with normoglycemia, impaired fasting glucose, and prevalent diabetes: results from the Rural Chinese Cohort Study. Journal of Epidemiology and Community Health.2018; 72(11):1052-1058.
(7)Yang Zhao, Yu Liu, Haohang Sun, Xizhuo Sun, Zhaoxia Yin, Honghui Li, Yongcheng Ren, Bingyuan Wang, Dongdong Zhang, Xuejiao Liu, Dechen Liu, Ruiyuan Zhang, Feiyan Liu, Xu Chen, Leilei Liu, Cheng Cheng, Qionggui Zhou, Dongsheng Hu, and Ming Zhang*. Association of long-term dynamic change in body weight and incident hypertension: The Rural Chinese Cohort Study. Nutrition.2018; 54: 76-82.
(8)Yang Zhao, Haohang Sun, Bingyuan Wang, Ming Zhang, Xinping Luo, Yongcheng Ren, Junmei Zhou, Chengyi Han, Chongjian Wang, Linlin Li, Lu Zhang, Chao Pang, Lei Yin, Tianping Feng, Jingzhi Zhao, and Dongsheng Hu*. Impaired fasting glucose predicts the development of hypertension over 6 years in female adults: Results from the Rural Chinese Cohort Study. Journal of Diabetes and Its Complications.2017; 31(7): 1090-1095.
(9)Yang Zhao, Ming Zhang, Xinping Luo, Chongjian Wang, Linlin Li, Lu Zhang, Bingyuan Wang, Yongcheng Ren, Junmei Zhou, Chengyi Han, Chao Pang, Lei Yin, Tianping Feng, Jingzhi Zhao, and Dongsheng Hu*. Association of 6-year waist circumference gain and incident hypertension. Heart.2017; 103(17): 1347-1352.
(10)Ming Zhang#,Yang Zhao#, Guoan Wang, Hongyan Zhang, Yongcheng Ren, Bingyuan Wang, Lu Zhang, Xiangyu Yang, Chengyi Han, Chao Pang, Lei Yin, Jingzhi Zhao*, and Dongsheng Hu*. Body mass index and waist circumference combined predicts obesity-related hypertension better than either alone in a rural Chinese population. Scientific Reports.2016; 6: 31935.
(11)Yang Zhao#, Ming Zhang#, Xinping Luo, Lei Yin, Chao Pang, Tianping Feng, Yongcheng Ren, Bingyuan Wang, Lu Zhang, Linlin Li, Hongyan Zhang, Xiangyu Yang, Chengyi Han, Dongting Wu, Junmei Zhou, Yanxia Shen, Chongjian Wang, Jingzhi Zhao*, and Dongsheng Hu*. Association of obesity categories and high blood pressure in a rural adult Chinese population. Journal of Human Hypertension.2016; 30(10): 613-618.
7.个人风采展示：
2020年心血管代谢性疾病流行病学随访调查项目启动仪式
2020年在美国杜兰大学博士联合培养期间（右：Jiang He教授）
