学校主页 |
劳动卫生与环境卫生学学科

张光辉

1.基本信息

张光辉,男,1982年出生,博士,副教授,硕士生导师,中国职业安全健康协会职业卫生专委会常委,中华预防医学会环境卫生分会委员,中国环境诱变剂学会青年委员,河南省预防医学会环境健康专业委员会常委。主要研究方向为重金属(铅)暴露对男性生殖健康及跨代遗传影响等。

2.教育经历

2010.9-2014.6,复旦大学公共卫生学院,博士学位,导师夏昭林教授。

2007.9-2010.6,郑州大学公共卫生学院,硕士学位,导师吴逸明教授。

2002.9-2007.6,河南医科大学公共卫生学院,学士学位。

3.科研与学术工作经历

2021/10-至今    陆军军医大学预防医学系

2020/7-2021/9   新乡医学院公卫 科研管理与学科建设办公室主任

2019/5-至今    新乡医学院 副教授

2016/11-2018/8  濮阳市人民医院(三甲) 挂职院长助理

2016/4—2016/6  陆军军医大学毒理所 进修

2014/6—2018/12  新乡医学院   讲师

4.主持或参加科研项目(课题)情况

2023/1-2026/12 国家自然科学基金面上项目“星形胶质细胞CaN/NFAT轴介导的GnRH神经元兴奋在铅致雄性生殖损伤中的作用”’(82273663)

2017/1-2019/12 主持国家自然科学基金青年项目“DNMT3A R882位点突变对苯致遗传损伤的甲基化机制研究”(81602836)

2018/1-2020/12 主持河南省科技厅科技攻关河南省男性生殖健康状况调查及重金属污染对其影响分析(182102310087)

2020/1-2021/12 主持教育部电磁辐射医学防护重点实验室开放课题,基于金属组学的男性生殖健康状况的危险因素探究(2018DCKF004)

5.代表性论文

(1). Xueshan Jia, Tingting Dong, Yufen Han, Zhongyi Yue, Pingyang Zhang, Jingchao Ren, Yongbin Wang, Weidong Wu, Huan Yang, Haibin Guo*, Guang-hui Zhang*, Jia Cao*, Identifying dose response relationship between seminal metal levels and semen quality by restricted cubic spline function, chemosphere.2022, 295: 133805. IF=8.9

(2). Zili Chai; Guang-hui Zhang; Xi Ling; Tingting Dong; Jingrong Wang; Yanqi Zhang; Peng Zou;Huan Yang; Niya Zhou; Qing Chen; Yuxin Zheng; Jinyi Liu; Jia Cao*; Lin Ao* ; Low-level and combined exposure to environmental metal elements affects male reproductive outcomes: Prospective MARHCS study in population of college students in Chongqing, China, Science of the Total Environment, 2022, 828:154395. IF=10.1

(3). Tuanwei Wang#, Yuting Tu#, Guanghui Zhang#, Shiyang Gong#, Kan Wang#, Yunxia Zhang, Yu Meng, Tongshuai Wang, Anqi Li, David C Christiani, William Au, Yiliang Zhu*, Zhao-Lin Xia*. Development of a benchmark dose for lead-exposure based on its induction of micronuclei, telomere length changes and hematological toxicity. Environ Int. 2021, 145:106129 (共同第一)IF=9.621

(4). Jing-chao Ren#, Huan Liu#, Guang-hui Zhang#*, Tongshuai Wang, Jingzhi Li, Tingting Dong, Hantian Wu, Zhao-lin Xia*. Interaction effects of environmental response gene polymorphisms and benzene exposure on telomere length in shoe-making workers. Chemosphere, 2020 Sep;255:126841. doi: 10.1016/j. Chemosphere.(共同通讯) IF=7.086

(5). Jingchao Ren, Junpeng Cui, Qing Chen, Niya Zhou, Ziyuan Zhou, Guang-Hui Zhang, Weidong Wu, Huan Yang*, Jia Cao*. Low-level lead exposure is associated with aberrant sperm quality and reproductive hormone levels in Chinese male individuals: result from the MARHCS, Chemosphere, 2020 Apr;244:125402.  doi: 10.1016/j.chemosphere.2019.125402.  IF=7.086

(6).Jing-chao Ren#, Tongshuai Wang#, Hantian Wu#, Guang-hui Zhang#*, Daoyuan Sun, Kongrong Guo, Haibin Li, Fengquan Zhang, Weidong Wu, Zhao-lin Xia*. The Promoter methylation in CSF3R influence peripheral neutrophils in benzene exposed poisoning, Environmental and Molecular Mutagenesis, 2020 Oct;61(8):786-796. (共同通讯) doi: 10.1002/em.22382. IF=3.216

(7). Guang-hui Zhang*, Jing-chao Ren, Mengkai Luo, Junpeng Cui, Yanqiu Du, Daokun Yang   Shouming Cui, Xiao Wang, Weidong Wu, Jia Cao*, Zhao-lin Xia*Association of BER and  NER pathway polymorphism haplotypes and micronucleus frequencies with global DNA methylation in benzene-exposed workers of China: Effects of DNA repair genes polymorphisms on genetic damage. Mutat Res. 2019 Mar;839:13-20. IF=2.256


代表作一览