袁金涛

讲师、硕士生导师

研究方向：计算毒理学、纳米材料制备及其应用、纤维化疾病机制

联系电话：0371-67781463

邮箱：jtyuan@zzu.edu.cn

一、基本介绍

袁金涛，男，1978年出生，讲师，医学博士，硕士生导师。现为劳动卫生与职业病学教研室教师。近年来主持和参与课题10余项，目前主持河南省高等学校重点科研项目基础研究计划项目1项，河南省重点研发与推广专项项目1项，河南省虚拟仿真实验教学系列项目1项，郑州大学教学改革类项目1项。迄今为止，以第一作者或通信作者发表SCI收录论文20多篇。

二、教育/工作经历

工作经历：

[1] 2016-至今，郑州大学，公共卫生学院，讲师

[2] 2008-2011，商丘医学高等专科学校，讲师

教育经历：

[1] 2013-2016，郑州大学，公共卫生与预防医学博士后流动站，博士后

[2] 2011-2013，东南大学，公共卫生学院，劳动卫生与环境卫生学，博士

[3] 2005-2008，南华大学，公共卫生学院，卫生毒理学，硕士

[4] 1998-2001，湖北药检高等专科学校，医学检验系，大专

三、主持科研项目

[1] 河南省高等学校重点科研项目（编号：23B330002；年限：2023-2024）：全氟/多氟烷基化合物经盐皮质激素受体途径促进高血压血管病变研究

[2] 河南省重点研发与推广专项（科技攻关）项目（编号：232102311047；年限：2023-2024）：细胞外基质硬度与低氧交互作用促进矽肺纤维化机制及维生素K3抑制作用研究

四、代表性成果

l 论文

[1] J. Ren, T. Jin, R. Li, Y.Y. Zhong, Y.X. Xuan, Y.L. Wang, W. Yao, S.L. Yu, J.T. Yuan*. Priority list of potential endocrine-disrupting chemicals in food chemical contaminants: a docking study and in vitro/epidemiological evidence integration, SAR and QSAR in Environmental Research, 2023, 34(10): 847-866.

[2] Yuyan Zhong, Jing Ren, Rui Li, Yuxin Xuan, Wu Yao, Qianye Yang, Yin Gan, Shuling Yu*, Jintao Yuan*. Prediction of the Endocrine disruption profile of fluorinated biphenyls and analogues: An in silico study. Chemosphere, 2023, 314, 137701.

[3] Zhenxia Lv, Jing Ren, Shaobo Zhang, Bokai Wang, Yuxin Peng, Wu Yao, Jintao Yuan*. Hologram QSAR and Topomer CoMFA Study on Naphthyridone Derivatives as ATAD2 Bromodomain Inhibitors. Current Chinese Chemistry, 2022, 2(3): e160522204804.

[4] Shaochen Wang, Qiaoqiao Zhou, Shuling Yu*, Shuang Zhao, Jiahua Shi*, Jintao Yuan*. Rod‑like hybrid nanomaterial with tumor targeting and pH‑responsive for cancer chemo/photothermal synergistic therapy. Journal of Nanobiotechnology, 2022, 20: 332.

[5] Shuling Yu, Jing Ren, Zhenxia Lv, Rui Li, Yuyan Zhong, Wu Yao, Jintao Yuan*. Prediction of the endocrine-disrupting ability of 49 per- and polyfluoroalkyl substances: In silico and epidemiological evidence. Chemosphere, 2022, 290: 133366.

[6] Qiaoqiao Zhou, Shaochen Wang, Peng Hu, Shuling Yu,* Jiahua Shi,* Jintao Yuan*. Targeted and Specific Modification with 4-Carboxybenzeneboronic Acid and TPGS of Fluorescent Gold Nanoparticles and the Enhanced Antitumor Activity Research. Particle and Particle Systems Characterization. 2021, 38(4), 2000333.

[7] Shuxin Jia, Shaochen Wang, Shanshan Li, Peng Hu, Shuling Yu*, Jiahua Shi*, Jintao Yuan*. Specific modification and self-transport of porphyrins and their multi-mechanism cooperative antitumor studies. Journal of Materials Chemistry B, 2021, 9(14): 3180-3191.

[8] S. Yu, S. Jia, D. Wang, Z. Lv, Y. Chen, N. Wang, W. Yao, J. Yuan*. Predicting pungency and understanding the pungency mechanism of capsaicinoids using TOPSMODE approach. SAR and QSAR in Environmental Research. 2020, 31(7): 527-545.